Episode 22:
Methemphetamine
Methemphetamine
BY HANNAH HENKEN
Methamphetamine abuse affects over twenty million individuals in the US, with users criminalized instead of seen as individuals struggling with a serious illness. Join us as we discuss how meth abuse affects an individual’s brain and life and what we can do as a country to help these individuals heal post-drug abuse.
This episode was produced as part of an upper level course on Neuropharmacology taught by Angel Kaur during Fall 2019 at UNC Asheville.
Articles Referenced
- Kish, S. J. Pharmacologic mechanism of crystal meth. CMAJ. 178(13), 1679-1682, (2008).
- Courtney, K. E.; Ray, L. A. Methamphetamine: an update on epidemiology, pharmacology,
clinical phenomenology, and treatment literature. Drug Alcohol Depend. 143, 11-21 (2014). - Twomey, J. et al. Prenatal methamphetamine exposure, home environment, and primary
caregiver risk factors predict child behavioral problems at 5 years. American Journal of
Orthopsychiatry. 83(1), 64-72 (2013). - Kohno, M. et al. Effects of naltrexone on large-scale network interactions in methamphetamine use disorder. Front Psychiatry. 10:603, 1-8 (2019).
- Guo, L. K. et al. Inhibition of naltrexone on relapse in methamphetamine self-administration
and conditioned place preference in rats. Eur J Pharmacol. [Epub ahead of print] (2019). - Lin, M. et al. Methamphetamine regulation of firing activity of dopamine neurons. J Neurosci.
36(40), 10376-10391 (2016). - Sudakin, D. Naltrexone: not just for opioids anymore. J Med Toxicol. 12(1), 71-75 (2016).
- Caprioli, D. et al. Role of dorsomedial striatum neuronal ensembles in incubation of
methamphetamine craving after voluntary abstinence. J Neurosci. 37(4), 1014-1027 (2017). - Karch, S. B. et al. Methamphetamine-related deaths in San Francisco: demographic,
pathologic, and toxicologic profiles. J Forensic Sci. 44(2), 359-368 (1999).
Related Reading
Kurtz, S. P. Post-circuit blues: motivations and consequences of crystal meth use among gay men in Miami. Aids and Behav. 9(1), 63-72 (2005).
Episode Transcript (PDF)
Credits
Written and Directed by: Hannah Henken
Featuring: Hannah Henken & Kati Henken
Scientific Research by: Hannah Henken & Zachary Kerkenbush
Additional Sound Engineering: Cat Sawyer
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