Episode 22:


Methamphetamine abuse affects over twenty million individuals in the US, with users criminalized instead of seen as individuals struggling with a serious illness. Join us as we discuss how meth abuse affects an individual’s brain and life and what we can do as a country to help these individuals heal post-drug abuse.

This episode was produced as part of an upper level course on Neuropharmacology taught by Angel Kaur during Fall 2019 at UNC Asheville.

Club Kaur
Club Kaur
22. Methamphetamine

Articles Referenced

  • Kish, S. J. Pharmacologic mechanism of crystal meth. CMAJ. 178(13), 1679-1682, (2008).
  • Courtney, K. E.; Ray, L. A. Methamphetamine: an update on epidemiology, pharmacology,
    clinical phenomenology, and treatment literature. Drug Alcohol Depend. 143, 11-21 (2014).
  • Twomey, J. et al. Prenatal methamphetamine exposure, home environment, and primary
    caregiver risk factors predict child behavioral problems at 5 years. American Journal of
    83(1), 64-72 (2013).
  • Kohno, M. et al. Effects of naltrexone on large-scale network interactions in methamphetamine use disorder. Front Psychiatry. 10:603, 1-8 (2019).
  • Guo, L. K. et al. Inhibition of naltrexone on relapse in methamphetamine self-administration
    and conditioned place preference in rats. Eur J Pharmacol. [Epub ahead of print] (2019).
  • Lin, M. et al. Methamphetamine regulation of firing activity of dopamine neurons. J Neurosci.
    36(40), 10376-10391 (2016).
  • Sudakin, D. Naltrexone: not just for opioids anymore. J Med Toxicol. 12(1), 71-75 (2016).
  • Caprioli, D. et al. Role of dorsomedial striatum neuronal ensembles in incubation of
    methamphetamine craving after voluntary abstinence. J Neurosci. 37(4), 1014-1027 (2017).
  • Karch, S. B. et al. Methamphetamine-related deaths in San Francisco: demographic,
    pathologic, and toxicologic profiles. J Forensic Sci. 44(2), 359-368 (1999).

Related Reading

Kurtz, S. P. Post-circuit blues: motivations and consequences of crystal meth use among gay men in Miami. Aids and Behav. 9(1), 63-72 (2005).


Written and Directed by: Hannah Henken 
Featuring: Hannah Henken & Kati Henken
Scientific Research by: Hannah Henken & Zachary Kerkenbush
Additional Sound EngineeringCat Sawyer

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