
Episode 29:
Investigating Ibogaine
Investigating Ibogaine
BY LAUREN KOZIK, BECKS LOGAN, JOE EULER
With America’s Opioid Epidemic in full swing, it is time that we look into the options that we have available to us. The current conventional ways in which we have historically dealt with this problem simply have not been working… at least not for everyone. This podcast will dive into an alternative medication that has proven to be effective in helping individuals get and stay off opioids with dramatic success: Ibogaine.
This episode was produced as part of an upper level course on Neuropharmacology taught by Angel Kaur during Fall 2020 at UNC Asheville.
Articles Referenced
- Alper, K. R., Lotsof, H. S., & Kaplan, C. D. The ibogaine medical subculture. J Ethnopharmacol., 115, 9-24. (2008).
- Davis, A. K., Barsuglia, J. P., Windham-Herman, A.-M., Lynch, M., & Polanco, M. (2017). Subjective effectiveness of ibogaine treatment for problematic opioid consumption
Short- and long-term outcomes and current psychological functioning. Journal of Psychedelic Studies, 1(2), 65–73. - Goldstein, Benjamin, “Political Chemicals: Drugs, Rights, and the Good Life.” Thesis, Georgia State University, 2017.
- He, D.‐Y. and Ron, D. (2006), Autoregulation of glial cell line‐derived neurotrophic factor expression: implications for the long‐lasting actions of the anti‐addiction drug, Ibogaine. The FASEB Journal, 20: 2420-2422.
- Hevesi, D. (2010, February 17). Howard Lotsof Dies at 66; Saw Drug Cure in a Plant.
- Johansen, P. Ø., & Krebs, T. S. (2015). Psychedelics not linked to mental health problems or suicidal behavior: A population study. Journal of Psychopharmacology, 29(3), 270-279.
- Lamb, R., Bachrach, L., Gabrielian, S., Bonfine, N., Livingston, J., Baillargeon, J., . . . Lin, C. (2001, August 01). Some Perspectives on Deinstitutionalization. Retrieved October 27, 2020.
- Lee, P. R., Lee, P. & Lee, D. 2010: U.S. Drug and Alcohol Policy, Looking Back and Moving Forward. ProQuest (2010).
- Levinson, J. (2018, April 11). Americans going abroad for illegal heroin treatment.
- Maciulaitis, R., Kontrimaviciute, V., Bressolle, F., & Briedis, V. (2008). Ibogaine, an anti-addictive drug: Pharmacology and time to go further in development. A narrative review. Human and Experimental Toxicology, 27(3), 181-94.
- Onaivi, E.S., Ali, S.F., Chirwa, S.S., Zwiller, J., Thiriet, N., Akinshola, B.E. and Ishiguro, H. (2002), Ibogaine Signals Addiction Genes and Methamphetamine Alteration of Long‐Term Potentiation. Annals of the New York Academy of Sciences, 965: 28-46.
- Rodger, J. (2011). The visionary cure of the addiction war? ibogaine: Social context, subcultural identity, and implications for drug policy. Drugs and Alcohol Today, 11(2), 77-89.
- Rubi, L., Eckert, D., Boehm, S., Hilber, K., & Koenig, X. (2017). Anti-addiction drug ibogaine prolongs the action potential in human induced pluripotent stem cell-derived cardiomyocytes. Cardiovascular Toxicology, 17(2), 215-218.
- Schenberg, E. E., de Castro Comis, M. A., Chaves, B. R., & da Silveira, D. X. (2014). Treating drug dependence with the aid of ibogaine: A retrospective study. Journal of Psychopharmacology, 28(11), 993-1000.
Credits
Written, Directed, and Featuring: Lauren Kozik, Becks Logan, Joe Euler
Scientific Research by: Lauren Kozik, Becks Logan, Joe Euler
Additional Sound Engineering: Cat Sawyer
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